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Exercise as an Intervention for Cancer-Related Fatigue

T Watson, PT, DPT, OCS, FAAOMPT, is Assistant Professor, Department of Physical Therapy, Western Carolina University, 319 Moore Bldg, Cullowhee, NC 28723 (USA) (twatson@email.wcu.edu).
V Mock, DNSc, RN, AOCN, FAAN, is Associate Professor of Nursing and Director of the Center for Nursing Research, Johns Hopkins University, and Director of Oncology Nursing Research, Kimmel Comprehensive Cancer Center at The Johns Hopkins Hospital, Baltimore, Md

Address all correspondence to Dr Watson

Key Words: Cancer • Exercise • Fatigue

Because this article has no abstract, we have provided an extract of the full text and any section headings.

	Introduction

 
Cancer-related fatigue (CRF) has been operationally defined by the National Comprehensive Cancer Network (NCCN) as a "persistent, subjective sense of tiredness related to cancer or cancer treatment that interferes with usual functioning."^1(p309) In people with no known pathology or limitations, fatigue is a universal human experience that is regarded as a basic protective mechanism against the depletion of metabolic energy reserves. With adequate rest, nourishment, and sleep, fatigue in these individuals is self-limiting. However, in contrast to exercise-induced fatigue experienced by these individuals, the fatigue experienced by patients with cancer is of greater magnitude and persistence, tends to remain after rest periods, is more disruptive to activities of daily living, and has a more negative affective impact.²

Until recently, medical advice for patients undergoing treatment for cancer was to obtain additional rest and avoid activities that are physically challenging. Currently, the use of exercise as an adjunct therapy for . . . [Full Text of this Article]

	Incidence

 

	Etiology

 

	Randomized Clinical Trials Testing Exercise on Patients With Breast Cancer

 

	Randomized Clinical Trial Testing Exercise on Patients With Hodgkin Disease

 

	Randomized Clinical Trial Testing Exercise on Patients With Prostate Cancer

 

	Recommendations for Exercise Programs for Patients With CRF

 

	Recommendations for Future Research

 

	Conclusion

 

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This article has been cited by other articles:

				J. L. Ryan, J. K. Carroll, E. P. Ryan, K. M. Mustian, K. Fiscella, and G. R. Morrow Mechanisms of Cancer-Related Fatigue Oncologist, May 1, 2007; 12(suppl_1): 22 - 34. [Abstract] [Full Text] [PDF]