HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Correction (v89,p103) All Versions of this Article: ptj.20080124v1 88/11/1345    most recent Submit a response Read responses to this article Alert me when this article is cited Alert me when Rapid Responses are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Marcus, R. L Articles by LaStayo, P. C Search for Related Content PubMed PubMed Citation Articles by Marcus, R. L Articles by LaStayo, P. C Related Collections Therapeutic Exercise Diabetes Related Webpages Social Bookmarking                      What's this?

Comparison of Combined Aerobic and High-Force Eccentric Resistance Exercise With Aerobic Exercise Only for People With Type 2 Diabetes Mellitus

RL Marcus, PT, PhD, is Associate Professor, Department of Physical Therapy and Department of Exercise and Sport Science, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108 (USA)
S Smith, MS, CDE, is Certified Diabetes Educator, Department of Physical Therapy, University of Utah
G Morrell, MD, PhD, is Assistant Professor, Department of Radiology, University of Utah
O Addison, PT, DPT, is Physical Therapist, Department of Physical Therapy, University of Utah
LE Dibble, PT, PhD, is Associate Professor, Department of Physical Therapy and Department of Exercise and Sport Science, University of Utah
D Wahoff-Stice, FNP, is Family Nurse Practitioner, Diabetes Center, University of Utah
PC LaStayo, PT, PhD, is Associate Professor, Department of Physical Therapy, Department of Exercise and Sport Science, and Department of Orthopedics, University of Utah

Address all correspondence to Dr Marcus at: robin.marcus{at}hsc.utah.edu

Background and Purpose: The purpose of this study was to compare the outcomes between a diabetes exercise training program using combined aerobic and high-force eccentric resistance exercise and a program of aerobic exercise only.

Subjects and Methods: Fifteen participants with type 2 diabetes mellitus (T2DM) participated in a 16-week supervised exercise training program: 7 (mean age=50.7 years, SD=6.9) in a combined aerobic and eccentric resistance exercise program (AE/RE group) and 8 (mean age=58.5 years, SD=6.2) in a program of aerobic exercise only (AE group). Outcome measures included thigh lean tissue and intramuscular fat (IMF), glycosylated hemoglobin, body mass index (BMI), and 6-minute walk distance.

Results: Both groups experienced decreases in mean glycosylated hemoglobin after training (AE/RE group: –0.59% [95% confidence interval (CI)=–1.5 to 0.28]; AE group: –0.31% [95% CI=–0.60 to –0.03]), with no significant between-group differences. There was an interaction between group and time with respect to change in thigh lean tissue cross-sectional area, with the AE/RE group gaining more lean tissue (AE/RE group: 15.1 cm² [95% CI=7.6 to 22.5]; AE group: –5.6 cm² [95% CI=–10.4 to 0.76]). Both groups experienced decreases in mean thigh IMF cross-sectional area (AE/RE group: –1.2 cm² [95% CI=–2.6 to 0.26]; AE group: –2.2 cm² [95% CI=–3.5 to –0.84]) and increases in 6-minute walk distance (AE/RE group: 45.5 m [95% CI=7.5 to 83.6]; AE group: 29.9 m [95% CI=–7.7 to 67.5]) after training, with no between-group differences. There was an interaction between group and time with respect to change in BMI, with the AE/RE group experiencing a greater decrease in BMI.

Discussion and Conclusion: Significant improvements in long-term glycemic control, thigh composition, and physical performance were demonstrated in both groups after participating in a 16-week exercise program. Subjects in the AE/RE group demonstrated additional improvements in thigh lean tissue and BMI. Improvements in thigh lean tissue may be important in this population as a means to increase resting metabolic rate, protein reserve, exercise tolerance, and functional mobility.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

Related Webpages:

This article has been cited by other articles:

				L. P Turcotte and J. S Fisher Skeletal Muscle Insulin Resistance: Roles of Fatty Acid Metabolism and Exercise Physical Therapy, November 1, 2008; 88(11): 1279 - 1296. [Abstract] [Full Text] [PDF]

				L. Stehno-Bittel Intricacies of Fat Physical Therapy, November 1, 2008; 88(11): 1265 - 1278. [Abstract] [Full Text] [PDF]

				T. N Hilton, L. J Tuttle, K. L Bohnert, M. J Mueller, and D. R Sinacore Excessive Adipose Tissue Infiltration in Skeletal Muscle in Individuals With Obesity, Diabetes Mellitus, and Peripheral Neuropathy: Association With Performance and Function Physical Therapy, November 1, 2008; 88(11): 1336 - 1344. [Abstract] [Full Text] [PDF]

				E. A. Gulve Exercise and Glycemic Control in Diabetes: Benefits, Challenges, and Adjustments to Pharmacotherapy Physical Therapy, November 1, 2008; 88(11): 1297 - 1321. [Abstract] [Full Text] [PDF]

				M. J Mueller People With Diabetes: A Population Desperate for Movement Physical Therapy, November 1, 2008; 88(11): 1250 - 1253. [Full Text] [PDF]