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Research Reports |
JW Brandsma, PhD, PT, is Research Associate, Dutch National Institute of Allied Health Professions, PO Box 1161, 3800-BD Amersfoort, the Netherlands (npi@pi.net).
BG Robeer, MD, is General Practitioner, Department of Cardiopulmonary Rehabilitation, Hart-en Longrevalidatiecentrum "Rijnlands Zeehospitium," Katwijk aan Zee, the Netherlands.
S van den Heuvel, PT, is Documentalist, Dutch National Institute of Allied Health Professions.
B Smit, PT, is Physiotherapist, Department of Cardiopulmonary Rehabilitation, Hart-en Longrevalidatiecentrum "Rijnlands Zeehospitium."
CHA Wittens, PhD, MD, is Vascular Surgeon, Sint Fransiscus Gasthuis, Rotterdam, the Netherlands.
RAB Oostendorp, PhD, PT, is Scientific Director, Dutch National Institute of Allied Health Professions.
Background and Purpose. There is no consensus about the indication for exercises for patients with intermittent claudication of the lower extremity and the characteristics of an exercise program to improve walking distance. The effect of walking is assessed by a systematic review of randomized clinical trials. Methods. Literature databases were accessed using the relevant key words. The references of identified articles were screened for additional studies. A checklist was developed to screen the studies with respect to the variables of interest. A methodological assessment form was developed to assess the methodological quality of the studies (maximum possible score: 100). Results. Eighty-two articles were identified, of which 21 studies were considered relevant for inclusion in the review. Following the analysis of the articles, 11 studies were for various reasons eliminated, leaving 10 studies for the systematic review. The score for methodological quality of the studies ranged from 47 to 75 (
=62.5, SD=8.5). Percentage of improvement in walking distance or time ranged from 28% to 210% (
=105%, SD=55.8%). Conclusion and Discussion. All studies showed that walking exercises improved walking distance in patients with intermittent claudication. Further research is needed to determine the optimal exercise program, the effect of adherence to the treatment protocol, and the duration of the effects following a formal exercise program.
Key Words: Exercises Intermittent claudication Meta-analysis Randomized clinical trial Review Walking
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Physical Therapy 1998 78: 286-288.
Physical Therapy 1998 78: 288.
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