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PHYS THER
Vol. 76, No. 7, July 1996, pp. 746-747

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Research Reports

Invited Commentary

Andrew J Robinson

AJ Robinson, PhD, PT, is Associate Professor, Department of Physical Therapy, School of Health Sciences and Human Performance, Ithaca College, 339 Smiddy Hall, Ithaca, NY 14850 (robby@ithaca.edu)

This excerpt was created in the absence of an abstract.

The research report by Bare et al on phonophoresis of hydrocortisone in humans describes a carefully implemented study designed to answer a very specific question: Does routine phonophoresis treatment with hydrocortisone acetate increase serum cortisol levels up to 15 minutes following treatment? The authors have accurately discussed the limitations of this work. First, they noted that the serum cortisol levels measured may not reflect actual tissue concentrations and that therapeutic levels of hydrocortisone may be present either in target tissues or stored nearby in fat or stratum corneum. The changes in tissue levels of drugs used in phonophoresis can be determined only by an assay of the tissue of interest....


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Related Articles

Phonophoretic Delivery of 10% Hydrocortisone Through the Epidermis of Humans as Determined by Serum Cortisol Concentrations
Anthony C Bare, Maire B McAnaw, Allyson E Pritchard, Jeffrey G Struebing, Michael A Smutok, Douglas S Christie, Manuel A Domenech, Mary A Bare, Marsha L Bloodworth, and Lawton A Seal
Physical Therapy 1996 76: 738-745. [Abstract] [PDF]

Invited Commentary
John L Echternach
Physical Therapy 1996 76: 747-748. [Abstract] [PDF]

Author Response
Anthony C Bare, Maire B McAnaw, Allyson E Pritchard, Jeffrey G Struebing, Michael A Smutok, Douglas S Christie, Manuel A Domenech, Mary A Bare, Marsha L Bloodworth, and Lawton A Seal
Physical Therapy 1996 76: 749. [Abstract] [PDF]






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Copyright © 1996 by the American Physical Therapy Association.